Semaglutide for laboratory research
A GLP-1 receptor agonist peptide. It is the active ingredient of licensed prescription medicines, so laboratory supply is tightly regulated and reviewed.
Overview
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist. Structurally it is an analogue of human GLP-1(7-37) with amino acid substitutions at positions 8 (Aib) and 34 (Arg), and a C-18 fatty diacid side chain attached to lysine 26 through a linker, which promotes albumin binding.
Semaglutide is the active pharmaceutical ingredient of licensed prescription medicines. NEXA does not supply medicines. Any research material enquiry is assessed against the requesting organisation, its research purpose and the destination country's controls.
Reference identity data
| Common name | Semaglutide |
|---|---|
| Class | GLP-1 receptor agonist (peptide) |
| Peptide backbone | 31 amino acids, analogue of GLP-1(7-37) |
| Molecular formula | C187H291N45O59 |
| Molecular weight (approx.) | 4113.6 g/mol |
| Typical form | Lyophilised powder (to be confirmed per batch) |
Values shown are standard literature reference values. Salt form, net peptide content, purity method and observed mass must be confirmed against the batch Certificate of Analysis.
Documentation available on request
- Batch-specific Certificate of Analysis, including the testing method, date and issuing laboratory
- HPLC purity with chromatogram, and mass spectrometry identity with observed and theoretical mass
- Net peptide content and salt form, where determined
- Batch number traceable to the vial label and invoice
No purity, testing or stock claim is published without supporting records. Read our guide on how to read a peptide Certificate of Analysis.
Regulatory status and eligibility
As the active ingredient of licensed medicines, semaglutide is subject to pharmaceutical regulation in many countries. Supply is considered only to qualified organisations, for non-clinical laboratory research, where the destination permits it.
Requests must come from a laboratory or research organisation and describe a legitimate non-clinical research purpose. Personal-use requests are declined. Import requirements in the destination country are the customer's responsibility.
Handling
For storage and handling of lyophilised material in the laboratory, see storing and handling lyophilised peptides.